Oral tolerance in disease
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چکیده
منابع مشابه
Oral glucose tolerance testing.
The oral glucose tolerance test (OGTT) is currently the gold standard for the diagnosis of diabetes. The recommended preparation for and administration of the OGTT are important to ensure that test results are not affected. Interpretation is based on venous plasma glucose results before and 2 hours after a 75 g oral glucose load.
متن کاملDevelopment of Oral Tolerance
"Oral (food) tolerance" usually describes a clinical situation that is not necessarily synonymous with the immunological definition of "tolerance," that is, as observed during development, transplantation or neonatal tolerance. In the context of this chapter, "oral tolerance" is defined as an antigen-specific immunological hyporesponsiveness after prior enteral administration. Oral exposure to ...
متن کاملOral iron tolerance.
The tolerance of volunteer patients to various ferrous salt preparations, administered orally in equivalent doses of elemental iron, has been compared. The palatability of ferrous sulphate tablets, BP, given before meals was not improved by administration after meals, by sustained release formulation, or by substituting other ferrous salts. Intolerance was related to the number of tablets rathe...
متن کاملMechanisms of oral tolerance revisited
Oral tolerance induction is thought to depend on special antigen presenting cells in the gut. A new report in the previous issue of Arthritis Research & Therapy supports this idea by demonstrating that indoleamine 2,3-dioxygenase-expressing dendritic cells in Peyer's patches from orally tolerized mice suppress T-cell responses via the generation of CD4+CD25+ regulatory T cells. This finding pro...
متن کاملRole of Regulatory Cells in Oral Tolerance
The immune system is continuously exposed to great amounts of different antigens from both food and intestinal microbes. Immune tolerance to these antigens is very important for intestinal and systemic immune homeostasis. Oral tolerance is a specific type of peripheral tolerance induced by exposure to antigen via the oral route. Investigations on the role of intestinal immune system in preventi...
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ژورنال
عنوان ژورنال: Gut
سال: 1999
ISSN: 0017-5749,1468-3288
DOI: 10.1136/gut.44.1.137